Bioorthogonal reagents with advanced properties

1 March 2017
Bioorthogonal reagents with advanced properties

We have discovered that 1,2,4-triazines bearing pyridinium substituents have interesting properties making these bioorthogonal reagents superior in many aspects. 

  • S. J. Siegl, R. Dzijak, A. Vázquez, R. Pohl, M. Vrabel, The discovery of pyridinium 1,2,4-triazines with enhanced performance in bioconjugation reactions, Chemical Science 2017, 8, 3593-3598, https://doi.org/10.1039/C6SC05442K 
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